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CRO/ CDMO Sub-Sectors Overview

Industry Definition

CRO/ CDMO companies support their clients in outsourced services. While CRO's typically help mainstream pharmaceutical companies with the first two stages of medication production (drug discovery and drug development), CDMO’s often help them with the second and third stages – drug development and drug manufacturing.

Foundation and Evolution of the Industry

The industry began to emerge in 1970s due to capacity issues in-house​ at the pharmaceutical companies


The late 1980s early 1990s witnessed arrival of blockbuster therapeutics and small biotech sector​


The combination of the two factors and increasing cost of drug development  changed the relationship dynamics of sponsor and service providers​


In 2018, value of CRO service market was estimated at $47 Bn, growing 7-9% CAGR through 2024 while CDMO was estimated at $98 Bn growing at 6-8% CAGR through the same period

Sponsors of Clinical Trials

Pharmaceutical ​Companies


Biotechnology​ Companies


Biopharmaceutical Companies


Medical Devices Companies ​


Sovereign Governments and their relevant agencies


Higher Education entities involved in therapeutic research


Sponsors Use CRO & CDMO Companies for:

Access to capabilities not found in-house​


Shift from fixed cost to variable cost model 


Improved global reach and access to patients​


Higher quality and more efficient execution​


Reduction in oversight required​


Lower capital requirements​


Accelerated development timelines & speed to market​


Access to process innovation not found internally​


Access to capacity

CRO Sub-Sector Overview

Market Size

Primary Customers

Primary Customers

  The CRO market is expected to grow from $47 billion in 2018 at a CAGR of 7-9% through 2024.

Primary Customers

Primary Customers

Primary Customers

  Small and Mid-Sized (SMID) pharma/bio/biopharma growth is driving the CRO market​.

Catalyst

Industry Progression

Industry Progression

  R&D spending growth, record-breaking biotech funding, increased CRO outsourcing penetration, and increased complexity in clinical development is expected to drive the CRO Market

Industry Progression

Industry Progression

Industry Progression

   

Outsourcing represented 47% of clinical development in 2013 and it is estimated to have surpassed 60% in 2020 with plenty of room to grow.

CDMO Sub-Sector Overview

Market Size

Growth Comparison

Growth Comparison

 The CDMO market is expected to grow from $98.7 billion in 2018 to $157.7 billion in 2025, at a CAGR of 6.9%.

Growth Comparison

Growth Comparison

Growth Comparison

 The growth of the CDMO market is looking to outpace the pharmaceutical industry altogether.

Catalyst

Industry Progression

Industry Progression

  The strong development of the CDMO market could be attributed to an increasing overall need for pharmaceuticals due to an aging societies in industrialized countries and better insurance coverage in developing countries. 

Industry Progression

Industry Progression

Industry Progression

   The future growth of the market will be highly attributable to an increasing willingness to outsource as a means todecrease time to market, save costs, reduce complexity, and reallocate internal resources. 

CRO/ CDMO Market Fragmentation

  

The CRO/ CDMO market is very fragmented, with less than 60 public companies globally and with most operating companies producing under $50 million in revenue​. 

  

Contract Research Organizations (CRO) and Contract Development and Manufacturing Organizations (CDMO) support life science R&D. They participate and execute in discovery, development and manufacturing of existing and novel drugs and therapeutics in clinical trials


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